Theo has been named Time Magazine's Luckiest Man Alive. For twenty consecutive years he has successfully bet double or nothing on the Super Bowl coin toss. And he's getting ready to risk millions on the twenty-first when he is confronted by Cynthia, a young woman who claims to have figured out his mathematical secret. Stem-cell researcher and professor Dr. Guzman is on the verge of a groundbreaking discovery. She’s also learned that one of her students has defied probability to get all 150 multiple-choice questions wrong on his genetics exam, but it’s not until he shows up to her office in the middle of the night that she’s able to determine if it’s simply bad luck. The two narratives intertwine like a double helix of DNA to examine the interplay between logic and metaphysics, science and faith, luck and probability. Belief systems clash, ideas mutate, and order springs from chaos. With razor-sharp wit and playful language, Sequence asks, in our lives, in our universe, and even in our stories, does order matter?